Hypercalcemia in Malignancy; the Second Great Masquerader

Hypercalcemia in malignancy can present with metabolic derangement, generalized weakness, altered mental status, renal compromise, cardiac dysrhythmias including atrial fibrillation and bradycardia, abdominal pain and/or shortness of breath amongst many other clinical manifestations. We present three cases of hypercalcemia in patients with malignancies; followed by discussion of hypercalcemia including etiology, clinical presentation and treatment.