Hussein, Mohammed Salah and Alshammari, Fozah sultan F. and Almutihi, Rayan Jahz N. and Fahad, H. Alrougi Abdullah and Busaleh, Hussain Ali and Saleh, S. Altammami Sultan and Shiha, Amal Mohsin Almaghribi and Alsalami, Suwaydi Essa and Harbi, Hussam Obaid Abdullah Al and Dhafer, Khadijah Nasr Aldeen M. and Alhammaqi, Fatimah Essa (2021) Overview of Scleroderma Renal Crisis - A Review. Journal of Pharmaceutical Research International, 33 (45A). pp. 334-340. ISSN 2456-9119
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Abstract
Scleroderma renal crisis is a life-threatening condition. It usually starts with a sudden onset of severe hypertension, followed by renal failure, hypertensive encephalopathy, congestive heart failure, and/or microangiopathic hemolytic anemia. Renal ischemia, hyperplasia of the juxtaglomerular apparatus, activation of the renin-angiotensin-aldosterone system (RAAS), and an increase in blood pressure are caused by decreased blood flow caused by structural changes in the blood vessels as well as renal vasospasm ("Raynaud's phenomenon"). This overview discusses the evaluation, diagnosis, and treatment of scleroderma renal crisis, emphasizing the importance of early detection of disease, strong correlation of corticosteroids intake and the disease incidence, and best approach of such cases.
Item Type: | Article |
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Subjects: | OA STM Library > Medical Science |
Depositing User: | Unnamed user with email support@oastmlibrary.com |
Date Deposited: | 14 Mar 2023 11:38 |
Last Modified: | 17 Jun 2024 06:51 |
URI: | http://geographical.openscholararchive.com/id/eprint/57 |